Hand and Brain -Neurorehabilitation-

Rehabilitation of Motor Function after Stroke: A Multiple Systematic Review Focused on Techniques to Stimulate Upper Extremity Recovery S amar M. Hatem 1, 2, 3 *, Geoffroy Saussez 2 , Margaux della Faille 2 , Vincent Prist 4 , XueZhang 5 ,DelphineDispa 2,6 andYannickBleyenheuft 2 1 Physical and Rehabilitation Medicine, Brugmann University Hospital, Brussels, Belgium, 2 Systems and Cognitive Neuroscience, Institute of Neuroscience, Université Catholique de Louvain, Brussels, Belgium, 3 Faculty of Medicine and Pharmacy, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium, 4 Physical and Rehabilitation Medicine, Centre Hospitalier de l’Ardenne, Libramont, Belgium, 5 Movement Control and Neuroplasticity Research Group, Motor Control Laboratory, Department of Kinesiology, Katholieke Universiteit Leuven, Leuven, Belgium, 6 Physical Medicine and Rehabilitation, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain...

Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice Yo Oishi, Qi Xu, Nature Communications 8, Article number: 734 (2017) doi:10.1038/s41467-017-00781-4 Motivation ,Neural circuits ,Non-REM sleep ,Sleep ,Slow-wave sleep Abstract   Sleep control is ascribed to a two-process model, a widely accepted concept that posits homoeostatic drive and a circadian process as the major sleep-regulating factors. Cognitive and emotional factors also influence sleep–wake behaviour; however, the precise circuit mechanisms underlying their effects on sleep control are unknown. Previous studies suggest that adenosine has a role affecting behavioural arousal in the nucleus accumbens (NAc), a brain area critical for reinforcement and reward. Here, we show that chemogenetic or optogenetic activation of excitatory adenosine A2A receptor-expressing indirect pathway neurons in the core region of the NAc strongly induces slow-wave sleep. Chemogenetic inhibition of th...

Clinically Important Differences for the Upper-Extremity Fugl-Meyer Scale in People With Minimal to Moderate Impairment Due to Chronic Stroke Stephen J. Page, George D. Fulk, Pierce Boyne Physical Therapy 2012   Background：The upper-extremity portion of the Fugl-Meyer Scale (UE-FM) is one of the most established and commonly used outcome measures in stroke rehabilitative trials. Empirical work is needed to determine the amount of change in UE-FM scores that can be regarded as important and clinically meaningful for health professionals, patients, and other stakeholders. Objective：This study used anchor-based methods to estimate the clinically important difference (CID) for the UE-FM in people with minimal to moderate impairment due to chronic stroke. Method：One hundred forty-six individuals with stable, mild to moderate upper-extremity (UE) hemiparesis were administered the UE-FM before and after an intervention targeting their affected UEs. The treat...

Therapeutic Synergism in the Treatment of Post-stroke Arm Paresis Utilizing Botulinum Toxin, Robotic Therapy, and Constraint-induced Movement Therapy Takashi Takebayashi, OTR, Satoru Amano, OTR, Keisuke Hanada, OTR,Atsushi Umeji, OTR, Kayoko Takahashi, OTR, ScD, Tetsuo Koyama, MD, PhD,Kazuhisa Domen, MD, PhD PM&R 2014 Botulinum toxin type A (BtxA) injection, constraint-induced movement therapy (CIMT),and robotic therapy (RT) each represent promising approaches to enhance arm motor re covery after stroke. To provide more effective treatment for a 50-year-old man with severe left  spastic hemiparesis, we attempted to facilitate CIMT with adaptive approaches to extend the  wrist and fingers using RT for 10 consecutive weeks after BtxA injection. This combined  treatment resulted in substantial improvements in arm function and the amount of arm use in activities of daily living, and may be effective for stroke patients with severe arm paresis.However, we were un...

rTMS treatments combined with speech training for a conduction aphasia patient  A case report with MRI study rTMS treatments combined with speech training for a conduction aphasia patient  A case report with MRI study Hui Zhang, MSa , Ying Chen, MSb , Ruiping Hu, MSb,c, Liqing Yang, PhDdJilei Zhang,PhDa , Haifeng Lu, MSa , Yi Wu, MDb,e,f,∗ Medicine 2017 Abstract Rationale: To date, little is known regarding the neural mechanisms of the functional recovery of language after repetitivetranscranial magnetic stimulation (rTMS) in aphasia. Our aim was to investigate the mechanism that underlies rTMS and speechtraining in a case report. Patient concerns and diagnoses: We report the case of a 39-year-old woman who was initially diagnosed with conductionaphasia following a left hemisphere stroke. Interventions: The rTMS location comprised the left Broca area, and a frequency of 5Hz for 20min/d for 10 days during a 2-weekperiod was used. She had received speech r...

Sensorimotor incongruence alters limb perception and movement Michihiro Osumi a , Satoshi Nobusako a , Takuro Zama b , Megumi Taniguchi a , Sotaro Shimada b , Shu Morioka a , ⁎ a Neurorehabilitation Research Center, Kio University, Nara, Japan b Department of Electronics and Bioinformatics, School of Science and Technology, Meiji University, Kanagawa, Japan ABSTRACT Altered limb ownership or heaviness has been observed in patients with hemiplegia, chronic pain, and several other conditions. Although these sensations are thought to be caused by sensorimotor incongruence, few studies have systematically veri fi ed this relationship. In addition, it remains unclear whether these subjective sensations a ff ect movement execution. In a psycho- physical experiment, we systematically investigated the relationships between sensorimotor in- tegration and subjective limb perception, such as sense of ownership/heaviness, and veri fi ed the relationship between subjective ...

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